바이오고분자실험실

Drug delivery system (DDS) using a polymeric micelle
Lipid - polymer system	PHB-mPEG micelle
＊Lipid (N-succinyl DPPE) Amphiphilic property polarity (hydrophilic) non polarity (hydrophobic) Important biomaterial ( the component of cell membranes )	＊Poly((R)-3-hydroxybutyrate) Hydrophobic property Biodegradable and biocompatible thermoplastic polymer
＊Poly(vinyl pyrrolidone) (PVP) Hydrophilic property Water soluble , biocompatibility	＊Poly(ethylene glycol) Hydrophilic property Water soluble, biocompatible
＊Model drug Hydrophobic drug (Anti-cancer)	＊Model drug Hydrophobic drug (Anti-cancer)

Introduction